Aarti Industries Ltd. [ company website ]

AARTI INDUSTRIES LIMITED (AIL) has world-class expertise in development & manufacturing of several basic chemicals, agrochemicals, specialty chemicals; and intermediates for pharmaceuticals & agrochemicals. It also has a specialised API manufacturing facility in the name of AARTI HEALTHCARE. AIL has its manufacturing activity at 5 different locations in States of Gujarat and Maharashtra in India. Presently we are making pharmaceutical intermediates in Custom Synthesis plant and cater to the needs of various Indian and International customers.

ABCR GmbH & Co. KG [ company website ]

ABCR is an established supplier of fine chemicals from catalogue up to bulk quantities. Together with abcr labs – a newly built contract manufacturing facility for specialty materials - we are now in the position to provide contract services for custom synthesis, product and process development as well as scale-up for the individual needs of pharmaceutical and chemical companies worldwide.

Adesis [ company website ]

Adesis Inc., a Delaware-based company, offers a range of chemistry services for early-stage to the leading life sciences companies. We provide support for early proof-of-concept projects, medicinal chemistry, lead optimization, custom syntheses and process development. We also specialize in the chemistry of orthogonally functionalized azaheterocycles (pyridines, azaindoles, piperidines and pyrrolidines). We aim to create value for our clients.

Aesica Pharmaceuticals [ company website ]

Aesica Pharmaceuticals is an innovative and service driven supplier of APIs, finished dosage forms and custom synthesis solutions to the global pharmaceutical and biotechnology industries. Aesica delivers products from the early-phase clinical development stage right through to commercial supply. Aesica also has the facilities for manufacturing high potency drugs and controlled substances.

Albemarle Corporation [ company website ]

Albemarle Corporation is a leading global developer, manufacturer, and marketer of highly-engineered specialty chemicals for consumer electronics, petroleum refining, utilities, packaging, construction, automotive/transportation, pharmaceuticals, crop protection, food-safety and custom chemistry services. The Company is committed to global sustainability and is advancing its eco-practices and solutions in its three business segments, Polymer Solutions, Catalysts and Fine Chemistry.

Allessa GmbH [ company website ]

The core technologies of AllessaSyntec are organometallic and low-temperature reactions down to ‑100 °C as well as high-pressure reactions up to 200 bar. Using our long term experience in the scale-up of a broad range of chemical reactions from laboratory process to industrial quantities, we offer multi-step exclusive syntheses in our multi-purpose facilities. In our 80 reactors sized 100 to 5,000 liters we are able to provide specialty chemicals from 10’s of kilograms up to 50 tons per year. Additionally our customers can take advantage of the large production capacities and broad technology portfolio of AllessaChemie. You are welcome to visit us at booth 79! For arranging a meeting during the conference, please contact by e-mail: RAmitrano@RAAAssociates.com

Almac Group [ company website ]

Almac Group provides world-class, integrated solutions to the global pharmaceutical and biotechnology industries. Our services include process R&D, custom synthesis of API; micronization, 14C radio-labeling, formulation and analytical development; commercial-scale manufacture; packaging; storage; QP release; supply chain management; diagnostic/genomic services, preparation of clinical supplies and technology solutions (IVRS /Web/EDC).

Alphora Research [ company website ]

Alphora Research Inc. provides API technology development services for the scale up of complex small molecules with pharmaceutical applications. Alphora's services include process development, analytical development and validation, stability testing and cGMP synthesis. Alphora's 40,000 sq.ft. facility includes cGMP Kilo Labs and Pilot Plant operations and supporting organic and analytical laboratories.

AMRI [ company website ]

Albany Molecular Research, Inc. (AMRI) is a global contract research and manufacturing organization offering customers fully integrated drug discovery, development, and manufacturing services. For over 21 years AMRI has demonstrated its adaptability as the pharmaceutical and biotechnology industries have undergone tremendous change in response to multiple challenges. This experience, a track record of success and locations in the United States, Europe and Asia now provides our customers with SMARTSOURCING^TM, a full range of value-added opportunities providing customers informed decision-making, enhanced efficiency and more successful outcomes at all stages of the pipeline. AMRI has also successfully partnered R&D programs and is actively seeking to out-license its remaining programs for further development.

APC [ company website ]

APC, The Applied Process Company, is the world's leading pharmaceutical process engineering research and development company. Through our proprietary research and technology programs APC works with innovator companies and CMOs (and their clients) to eliminate process engineering barriers from pre-clinical to late stage process development and next generation manufacture. Our core expertise includes reaction engineering and process modelling, distillation and extraction design, crystallization and particle property design and tuning and delivery of scale independent operations and processes. Our proprietary technologies and services include:

ACHIEVE ^TM / BioACHIEVE ^TM        Data and model driven mg to kg process engineering

iQbD+ ^TM                                            Advancing process understanding

Ash Stevens [ company website ]

Ash Stevens is an established pharmaceutical contractor that develops, registers, and manufactures Active Pharmaceutical Ingredients (APIs). Founded in 1962, Ash Stevens has a long and successful history of delivering APIs on time and on budget. Behind our success is an experienced team of talented scientists and regulatory experts committed to providing the highest quality of service. Ash Stevens offers a comprehensive and flexible package of manufacturing services to support early-stage development, FDA registration, and commercialization.

BCN Peptides [ company website ]

BCN Peptides is focused on the cGMP Industrial Manufacture of Bioactive Peptides for Pharmaceutical applications. We manufacture from gram until multi-kilo batches of GMP Peptide using SPPS technology. Excellent GMP compliance track record: FDA and EDQM Approved. We manufacture from the R&D, through batches for the Clinical Trials, up to Bulk Commercial Quantities. Moreover we have been authorized (since March 2010) to work as Pharmaceutical Laboratory for the Quality Control of final Drug Product.

BioTools, Inc.

Leaders in the field of chirality and biopharmaceuticals, the first to introduce instrumentation and lab services for Vibrational Circular Dichroism (VCD) and Raman Optical Activity (ROA). ChiralIR-2X VCD Spectrometer is the most sought-after technique for the determination of absolute configuration (AC), determination of enantiopurity (%EE) and solution conformations. VCD is used by pharmaceutical industry and regulatory agencies worldwide for fast and easy AC answers. VCD is a solution-state measurement and requires no chiral separation, derivatization or crystallization. The ChiralRaman-2X combines ROA with Raman microscopy for analysis of proteins, viruses, sugars and nucleotides; PROTA FT-IR for secondary structure and formulations, primary choice for biopharmaceutical formulations; Micro-imaging Raman Spectrometer designed for fast easy measurements of biologics and applications of SERS. BioTools provides a complete line of Spectroscopic accessories and software, our Contract Lab provides services for the characterization of chiral molecules and proteins.

Buchi Pilot Plant & Reactor Systems [ company website ]

Buchi glass equipment and pharma reactor systems guarantee best performance in R&D, pilot plant, kilo lab and production - for scale up studies to cGMP manufacturing of API’s and chemicals. Chemical reactions, full vacuum distillation a.o. are performed safely; nutsch filters, glass mixing vessels and scrubbers are availble for additional process steps.

C&EN [ company website ]

C&EN is the largest weekly newsmagazine serving the chemical and life sciences industry for over 85 years. Each week, C&EN reports on the latest business and science news of interest to more than 161,000 readers representing executive managers, scientists, and those involved in R&D in the top labs in the U.S. and around the world. C&EN is the global advertising leader and publishes more than 40 special reports on pharmaceutical outsourcing, biopharmaceuticals, and pharmaceutical partnering to name a few. C&EN offers companies electronic advertising opportunities including co-branded Webinars, contextual & interstitial advertising, and high visibility online advertising

Cambridge Major Laboratories [ company website ]

Cambridge Major Laboratories is a leading global chemistry outsourcing partner to the pharmaceutical and biotechnology industries, producing pharmaceutical intermediates and Active Pharmaceutical Ingredients. The Company has experienced explosive growth the past decade, and boasts a long, successful FDA inspection history. CML operates from three facilities in the US and Europe.

Central Glass Germany [ company website ]

Central Glass Germany is dedicated to process development, upscaling and production of active ingredients and intermediates for the pharmaceutical and cosmetics industry. It operates a FDA and EU inspected facility in Halle-Künsebeck, which it acquired from Girindus in June 2008. An experienced and highly skilled team of organic chemists and support functions, such as analytical specialists and QA/QC team, ensure success and high quality of our projects.

Chemistry Today [ company website ]

Fine chemicals, pharma chemistry, biotechnology: these are the main topics of Chimica Oggi/Chemistry Today specially addressed to a readership belonging to the industrial field. Funded in 1983 and considered one of the most credited journals in its sector, it boasts an ever increasing circulation worldwide, thanks to its highly scientific articles suitable for industrial applications. Chimica Oggi/Chemistry Today is essential to those who are looking for updated, accurate, reliable information; specially for those making the word “innovation” the keyword to their own mission.

Every issue includes one or more monographic inserts entirely devoted to one specific subject. These inserts are being more and more appreciated by our readers as they can find in their pages a precious help to their constant commitment to the research and development field.

Chiral Quest Corp. [ company website ]

Chiral Quest is a US-based company founded in 2000 and Jiangxi Long Life was founded in 2009 near Nanchang, China. In May 2012 Chiral Quest and Long Life merged to form a single company. Chiral Quest Suzhou is focused on R&D and pilot plant operations and Chiral Quest Long Life is focused on commercial scale manufacture. The combined company has more than 100,000 L of manufacturing capacity, with expertise in high pressure asymmetric hydrogenation and cryogenic reactions. The company has successfully developed and scaled up many processes for the commercial manufacture of both chiral and achiral intermediates. The combination of Chiral Quest’s chiral technology portfolio and Long Life’s low-cost manufacturing provides a unique service offering in China.

Chiral Technologies, Inc. [ company website ]

Chiral Technologies, Inc. (CTI) is the market leader in the area of enantioselective chromatography. Together with Daicel Corporation, we support all stages of the single-enantiomer drug development process from preclinical studies to commercial drug development. We offer a full range of chiral HPLC and SFC chromatography columns for analytical, semi-preparative and preparative separations. To accelerate drug development efforts, we provide the enantioselective resolution of quantities ranging from 200 milligrams to 200 kilograms of chiral compounds, under cGMP if required. We also provide process development and pilot studies for the manufacture of chiral intermediates of approved drugs.

Crystallics [ company website ]

Crystallics’ expertise is in the area of solid state research and pre-formulation. Crystallics is a CRO specializing in the optimization of the drug substance physical forms including salts, polymorphs, amorphous forms and co-crystals. We also assist with the scale-up crystallization process, miniaturization and troubleshooting in the crystallization process. Our services are based on unique and proprietary hardware and software technologies and these technologies together with strong customer focus has established Crystallics as the number one independent service provider in solid state research.

Daikin America [ company website ]

For almost a century, since 1924, Daikin has been a world leader in the development, manufacture and sales of fluoropolymers, fluoroelastomers, fluorochemicals, and fluorocoatings. Headquartered in Osaka, Japan, Daikin is renowned for innovation, quality products and customer commitment. With manufacturing, sales, and technical support located in 9 countries throughout the world and with over 36,000 employees in North America, South America, Europe and Asia, Daikin has a strong global foundation

Delmar Chemicals, Inc. [ company website ]

Delmar specializes in process development and custom cGMP synthesis of APIs and advanced intermediates. Delmar has well-equipped Process R&D and Analytical R&D laboratories, a cGMP pilot plant and a cGMP commercial-scale production facility. In addition, Delmar offers a full range of custom development and manufacturing services including process development and validation, analytical method development and validation, ICH stability studies and comprehensive regulatory support including the preparation of CMC sections and Drug Master Files.

DIVERCHIM [ company website ]

DIVERCHIM is a privately owned company engaged in innovative chemistry based drug (and materials) discovery and development. We offer a broad range of integrated organic chemistry R&D capabilities and our proprietary technologies to pharmaceutical, biotechnology, agrochemical, and cosmetic companies.

DIVERCHIM is committed to carrying out the customer's confidential contract research on a fee for service basis without downstream royalty payments. We assure complete confidentiality and technology transfer in the case of exclusive methodology development. Since January 2000, Diverchim has conducted R&D projects in collaboration with more than 20 pharmaceutical and biotechnology companies throughout the EC. Our Strengths include the highest scientific and quality standards, strong emphasis on customer service, excellent scientific staff and technology capabilities.

Dottikon Exclusive Synthesis [ company website ]

DOTTIKON EXCLUSIVE SYNTHESIS is specialized on hazardous chemistry, with a focus on strongly exothermic reactions as well as unstable, highly reactive, or high-potent compounds or mixtures. DOTTIKON ES manufactures high-quality intermediates and exclusive APIs, from the kilogram to the multi-ton range, for the world's leading pharmaceutical and chemical industries. Hazardous reactions often allow to shorten production and synthesic procedures, reduce waste, improve yields, selectivity, and purity, and therefore reduce overall costs. Among the core strengths of DOTTIKON ES are: hazardous reactions, such as reductions with complex hydrides, alkylations, azide chemistry, nitrations and oxidations. As well as heterogeneous and homogeneous catalytic hydrogenations, continuous reaction technologies and low temperature reactions.

Euticals SpA [ company website ]

Euticals is a privately held pharmaceutical fine chemical manufacturer. We manufacture APIs in a broad range of therapeutic classes at 11 sites in the US and western Europe; 10 of these sites are cGMP. The chemical technology portfolio includes: organometallic chemistry, fermentation, bulk sterile production, nucleotides, peptides, HAPIs and cytotoxics. Consider Euticals, with our broad range of capabilities and expertise, to assist in your next outsourcing challenge.

Evocatal [ company website ]

evocatal is a German provider of enzyme technology and biocatalytical processes. The company offers a catalog of ready-to-use enzymes (evozymes) and chiral building blocks but also offers the customized development of exclusive biocatalysts and chemical processes, tailored to match the unique demands of our customers. evozymes are applied in API- and intermediate synthesis, but also in consumer goods industries, including the production and refinement of textiles, adhesives, detergents, nutrition and cosmetics. Our enzymes and chiral building blocks can be provided in every scale.

Evonik [ company website ]

Evonik offers a full range of custom manufacturing services as well as formulation development expertise. Our global footprint and expertise provide flexibility and problem solving capabilities to meet your project’s unique requirements.

As a leader in HPAPI manufacturing, we can take your project from lab scale through to large commercial multi-ton quantities. At our facility in Lafayette, IN, which has been producing commercial quantities of HPAPIs for two decades, we operate with OELs <0.1 µg/m3. We have experienced people with the right expertise, the right equipment and the right motivation to see your high potency projects from clinical stages through commercialization.

Our experience also includes the manufacture of non-exclusive intermediates and APIs such as L-tert-leucine based building blocks, Lisinopril, Lorazepam and Nifedipin. We can offer amino acids, derivatives, and small chain peptides for perenteral or oral nutrition, or as building blocks for synthesis.

For your formulation needs, we produce excipients for oral application (Eudragit) and Bioresorbable polymers for injected extended release formulations or medical devices (Resomer, Lakeshore Biomaterial). We offer formulation development for oral and injectable forms with expertise in solubility and bioavailability enhancement of oral formulations - via spray drying, Hot Melt Extrusion or proprietary technologies - from preclinical to early clinical phases. And we have expertise in injectable extended release formulation – microsphere, gel or implants – from preclinical to commercialization.

Evotec [ company website ]

Evotec is a drug discovery alliance and development partnership company focused on rapidly progressing innovative product approaches with leading pharmaceutical and biotechnology companies. We operate worldwide providing the highest quality stand-alone and integrated drug discovery solutions, covering all activities from target-to-clinic. The Company has established a unique position by assembling top-class scientific experts and integrating state-of-the-art technologies as well as substantial experience and expertise in key therapeutic areas including neuroscience, pain, metabolic diseases as well as oncology and inflammation. Evotec has long-term discovery alliances with partners including Boehringer Ingelheim, CHDI, Genentech, Medimmune/Astra Zeneca, and Ono Pharmaceutical. In addition, the Company has existing development partnerships and product candidates both in clinical and preclinical development. These include partnerships with Boehringer Ingelheim, MedImmune and Andromeda (Teva) in the field of diabetes, and with Roche in the field of Alzheimer's disease.

Farmabios [ company website ]

Farmabios manufactures and markets Active Ingredients for pharmaceutical applications (API - Active Pharmaceutical Ingredients) in highly specialized groups: Steroids, Sterile Steroids, Semi-synthetic cephalosporins, Sterile semi-synthetic cephalosporins, Highly Potent Substances, Antineoplastics.

Thanks to the wide range of advanced proprietary technologies available, Farmabios provide custom synthesis services to companies specializing in the identification and development of New Chemical Entities (NCEs). Farmabios operates in compliance with cGMP standards and is subject to regular inspections by international Regulatory Agencies such as FDA and EDQM

Farmhispania [ company website ]

Farmhispania develops and manufactures under cGMP APIs / HAPIs for both oral and injectable formulations. Between other therapeutic areas, Farmhispania has core expertise in ACE inhibitors and Neuromuscular blocking agents. Farmhispania supports Brand sector under strict confidentiality and on exclusive basis.

Fermion [ company website ]

Welcome to Fermion! We are one of the leading companies active in API’s for the innovative and generic drugs industry. Founded in 1969 as a company developing products through fermentation and being a daughter company of Orion Corporation, we offer Contract Research and Manufacturing Services to third parties worldwide. Ten innovative products, for which Fermion developed the API, have either been filed or launched/commercialized worldwide.

We offer partnering for in-licensing and co-marketing, contract manufacturing for dosage forms, contract manufacturing for small-scale APIs and being competitive in the API space by co-operating with partners for procuring early intermediates. We have two FDA-inspected plants and manufacture more than 220 tons of API per year.

Ferro Corporation [ company website ]

Ferro Pfanstiehl Laboratories, Inc. is based in Waukegan, Illinois and manufactures commercial quantities of specialty and blocked sugars,high-purity low-endotoxin carbohydrates, pharmaceutical intermediates, and high-potency active pharmaceutical ingredients under current good manufacturing (cGMP) conditions and has more than 20 active US and international Drug Master Files.

Fuji Chemical Industry Co., Ltd. [ company website ]

Fuji Chemical Industry is a pharmaceutical contract manufacturer with cGMP facilities for production of API, spray drying and finished dosage forms. We have particular expertise in spray drying which can be used to improve API properties and develop amorphous solid dispersions for increased drug solubility and bioavailability. We have world-class capabilities developed over decades of experience and offer customized services to support projects from early-stage development through commercial production, including custom formulation services.

Gelest, Inc.

Gelest Inc. is recognized world-wide as a leader and innovator in materials science and technology. Gelest manufactures and provides organosilicon and metal-organic compounds serving advanced technology markets though a customer driven approach. Please visit www.gelest.com for more information.

GVK BIO [ company website ]

GVK Biosciences (GVK BIO) is Asia’s leading Contract Research Organization. With a vision to be a global leader in life sciences research and services, GVK BIO offers a spectrum of stand-alone and integrated services across the life sciences R&D value chain. Our discovery services consist of Analytical Services, Chemistry Services, Biology and Informatics, while the Development Services include Clinical Research, Medical Affairs, Clinical Pharmacology, Analytical Development, Process R&D, Custom Synthesis and Contract Manufacturing. GVK BIO works with a large and diverse set of customers from leading pharmaceutical companies, biotechnology organizations, virtual companies, agro chemical industries to research institutions & universities throughout the R&D process.

Hamari Chemicals USA [ company website ]

Hamari Chemicals, Ltd. is a global provider of custom chemical manufacturing to the pharmaceutical industry. We have extensive experience in the synthesis and production of active pharmaceutical ingredients (APIs) and advanced chemical intermediates. Our core strengths include, synthesis of amino acid derivatives, small molecules, heterocycles, peptides, chiral intermediates, and performing transition metal mediated coupling reactions on the commercial scale. Whether your project is at the discovery stage, pre-clinical stage, clinical stage, or ready for commercial production we have the experience and expertise to help your company through the API development process.

Helsinn [ company website ]

Helsinn Chemical Operations develop and manufacture APIs, cGMP Advanced Intermediates and High Potency Active Ingredients (HPAIs) for third parties from early phases to commercial supply on an exclusive basis. The production plants are located in Switzerland and Ireland, with the Swiss plants successfully inspected by the FDA (with no 483 observations). Scale is from few hundreds of grams (HPAIs), up to tens of tons for APIs in plants fully dedicated to cGMP manufacturing.  Long-term experience in management of the CMC part and full regulatory support is available for our partners. Helsinn’s expertise along with our reputation with the Authorities will speed-up the registration of our partner’s NCE.

Hengdian Group [ company website ]

Hengdian Group was established in 1975 and is now a multinational company and one of the largest privately owned companies in China. The Pharmaceutical and Chemical division has three factories and over 3500 employees, with 2 of them having passed an FDA audit. Our products include intermediates, API’s as well as other speciality chemicals. We have worked with many multinational companies in contract manufacturing for over 10 years. We aim to be efficient, flexible, and fast, offering the best service and quality to our customers.

Heraeus Precious Metals GmbH [ company website ]

Heraeus has more than 25 years experience in the development and production of high potency oncology APIs. Today, Heraeus offers a unique variety of technical expertise in its state-of-the-art facilities, from chemistry to fermentation processes. Regular inspections by the U.S. FDA as well as other authorities support Heraeus’ main objective of delivering high quality Contract Development and Manufacturing services.

Heraeus is a globally active precious metal and technology Group based in Hanau, near Frankfurt, and with deep roots in Germany. The company has been family-owned for 160 years. In 2010, on the strength of more than 12,900 employees in more than 120 companies, Heraeus generated product revenues of €4.1 billion and precious metals trading revenue of €17.9 billion.

Hybio Pharmaceuticals [ company website ]

Hybio is a hi-tech enterprise specialized in the R&D and manufacturing of diverse peptide products. Founded in 1998, after over decades of effort, we have grown to be one of the largest and most professional peptide pharmaceutical company in China. We were one of the first to enter the peptide pharmaceutical industry in China, and we are the only one that has a full range of peptide products and services, including peptide finished dosage products, peptide API products, and peptide CRO&CMO services. Our peptide finished dosage is mainly sold in the domestic market, but some of our peptide APIs have been supplied to customers all over the world. Hybio is a GMP-approved pharmaceutical company. Our GMP plant in Shenzhen is a facility occupying an area of more than 1,5000 sq.m. It has been often audited and inspected by local/national s-FDA authorities and by clients all over the world.

IRIX Pharmaceuticals [ company website ]

IRIX Pharmaceuticals is a recognized CRO/CMO specializing in Small Molecule APIs and Advanced Intermediates. IRIX has the expertise and experience to solve very complex chemistry challenges while meeting aggressive clinical delivery timelines. IRIX has High Containment, High Pressure, Cryogenic, Beta-Lactam and Controlled Substances capabilities. We have two US facilities both of which have been successfully inspected by the FDA along with additional laboratory facilities in St. Petersburg, Russia.

J-Star Research [ company website ]

J-STAR Research, J-STAR, based in South Plainfield, NJ is capable of tackling some of the most challenging chemistry problems in the industry including developing optimal synthetic routes, process research, scale up, synthesis of metabolites and impurities, developing novel synthetic strategies and cGMP manufacturing. The company was founded by a Dr. Andrew Thomson from Merck over ten years ago.

Johnson Matthey [ company website ]

Johnson Matthey Pharma Services provides API outsourcing solutions throughout the drug development process. With over 35 years’ experience and more than 125 professionals in the Boston area, our services encompass all areas of research, development, and cGMP manufacturing. Strong regulatory compliance underscores our services for custom synthesis, PR&D, scale-up, optimization, and validation of new chemical entities (NCEs). Beyond traditional chemistry services, we provide solutions for complex molecules via separation technologies, asymmetric/chiral development and analytical technologies, catalytic process screening, and solid form screening. JMPS’ services are retained for a variety of compounds including small molecules, natural products (extraction), controlled drug substances, and highly potent active ingredients. Our Devens, MA facility offers manufacturing scale ranges from grams to hundreds of kilograms. To round out these services, our regulatory department has an impeccable track record with FDA audits (including PAI’s) and provides CMC support to our client's regulatory filings. JMPS’ sister companies, JM Pharmaceutical Materials and Alfa Aesar, round out the Pharma division with additional manufacturing capacity, commercial API production, and fine chemical products.

Kalexsyn, Inc. [ company website ]

Kalexsyn provides clients with proven, experienced medicinal chemists: IP-enabling SAR, custom synthesis, stable label synthesis, early API scale-up and process improvement. Full analytical capabilities onsite. We deliver:

• Real medicinal chemistry: Medchem experience built from years of experiential practice.
• Problem solving: Able to problem solve tough synthetic challenges in conjunction with clients. You can ask them.
• Communication: Information provided in an agreed upon format, on time every time. Our international client base from Osaka to Vienna is reflective of our successful communication skills.

Kaneka Americas [ company website ]

Utilizing enzyme-mediated synthesis and fermentation technology along with a wide variety of advanced organic synthetic methodologies, Kaneka has established itself as a leading innovator and reliable manufacturer of chiral pharmaceutical intermediates and fine chemicals.

Lacamas Laboratories [ company website ]

Lacamas Laboratories, Inc. custom manufactures pharmaceutical intermediates and other fine chemicals for use outside the pharma industry. Our commitment to quality standards is evident in our production processes, laboratory procedures, raw material procurement and testing, R&D, implementation of production and laboratory standard operating procedures, and final product testing.

Lonza [ company website ]

Lonza offers the life sciences market a full range of products, flexible development services and high-quality manufacturing for functional and active ingredients. For 30 years Lonza Custom Manufacturing has been helping emerging and established companies increase product quality, improve production processes, navigate the development and regulatory process, lower the cost of goods, get to market faster, and focus on their core competencies. From lead optimization and early development through launch to commercial leadership and mature market supply, our complete development services, industry-leading manufacturing processes, broad technology platform and lifecycle management experience can help take your product to the next level. For flexible, high-quality contract manufacturing, development services and products, we can help. Together … turning promising discoveries into viable products.

Manchester Organics Limited [ company website ]

For over 40 years, a global leader in fluorination & high pressure technology, research and manufacturing.  From our locations in the UK, India and USA we have built valued relationships spanning all areas of the chemical industry, ranging from pharmaceuticals to electronics. Our manufacturing capabilities range from R&D through to commercial scale production and we also offer a continually expanding catalog of building blocks and fine organic chemicals. Our specialism in fluorination technology together with expertise in general organic synthesis at all scales (cGMP and non-cGMP) allows us to bring an extensive range of fine chemicals to you through our catalog, as well as servicing a wide, chemically diverse range of custom synthesis, development and scale-up projects.

For more information contact -  Ajay K. Ohri, Global Head of Business Development at (908) 300-2196 or  ajay.ohri@nfil.in

Mercachem [ company website ]

Mercachem is a privately owned leading European contract research organization offering innovative exploratory chemistry, medicinal chemistry and process R&D services to accelerate the drug discovery and development process in a flexible and cost-effective way. Mercachem was founded in 1997, occupies 3,500 m2 state-of-the-art research facilities in Nijmegen, the Netherlands, and employs more than 100 chemists. Working for many pharmaceutical and biotech companies throughout the world, Mercachem is recognized for its high-quality products and services and its unprecedented problem solving capabilities.

Exploratory chemistry
• Development of novel chemistry methodology
• Single compound synthesis (reference compounds, impurities, metabolites etc.)
• Parallel synthesis of small focused libraries

Medicinal chemistry

• Design and synthesis of druglike molecules
• Hit, hit-to-lead and lead optimization
• Structure-guided lead generation

Process Research

• Route scouting
• Catalyst screening
• Reaction and process optimization
• Material supply (~ 1 kg)

Micron Technologies Inc [ company website ]

Micron Technologies provides contract particle size reduction and analytical services for the pharmaceutical and biotech industries. We offer micronization, mechanical milling, and classification in isolated processing suites. Our analytical laboratory offers material characterization testing, including but not limited to, particle size, TGA, DVS, XRPD, DSC, stability, method development and validation. US and UK facilities are FDA inspected.

Navin Fluorine International Ltd. [ company website ]

Navin Fluorine International Ltd. (NFIL, >40 years, >US$98M, public company in India) has extensive expertise in specialty fluorine chemistry and fluorination services. NFIL invested to grow our offerings with a state-of-the-art R&D center (2008 and Dec 2010), pilot plant (2009), new multi-product plant (July 2010), cGMP pilot plant (Feb 2011), and full cGMP production facility (late 2011). NFIL launched its Contract Research division for full CRAMS (Contract Research and Manufacturing Service) support. We can synthesize individual compounds, libraries, or scaffolds, and also efficiently develop processes from lab, to pilot, to commercial. FluorosimilarsT services offer fluorine analogs of desired targets. NFIL provides custom synthesis and toll manufacturing from mg/g to full multi-ton commercial scales (plus commercial fluorination reagents, intermediates, etc.) via almost all fluorination methods including HF, Halex, electrochemistry, and even a proprietary alternative to DAST, just to name a few. For more information contact Jeffery S. Hinkle, Ph.D., MBA, Global Head of Business Development, 732-377-3362, Cell: 908-304-3562, or jeffery.hinkle@nfil.in.

Nissan Chemical Industries [ company website ]

Nissan Chemical Industries provides custom manufacturing and process development services for APIs and their intermediates from pre-clinical to commercial production stages. In addition, we offer analytical method development, stability testing, and filing of DMFs. Our company has various technologies for asymmetric synthesis, such as epoxidation, anti-selective hydrogenation, aldol reaction, and Michael reaction, for manufacturing optically active substances. We also have been working on AZADO, an ultra-highly active catalyst for alcohol oxidation, for commercial development.

NovAliX [ company website ]

NovAliX is focusing on the development of enabling chemistry and biophysical technologies to support the pharmaceutical industry’s outsourcing needs from discovery to manufacturing. With proprietary unique SPR technology, X-ray protein crystallography, supramolecular mass spectrometry and chemistry NovAliX offers comprehensive integrated services for small molecule drug discovery. With advanced NMR technologies, NovAliX provides fine characterization of biologics, thorough analysis of APIs and polymorphism studies to support pharmaceutical development and manufacturing teams. NovAliX Group, a team of 120 scientists, is located in state-of-the-art laboratory facilities in Strasbourg-Illkirch (France) and Heidelberg (Germany).

Novasep [ company website ]

Novasep develops, markets and operates innovative technologies to produce synthetic molecules from lab to industrial scale. Our applications cover the pharmaceutical, agrochemical and fine chemical markets. We offer contract synthesis and purification in 6 FDA-inspected facilities for early development, clinical and commercial scale (up to several hundreds of tons), with full regulatory support.
 

Our process development teams select, develop and optimize synthetic and purification routes to provide you with cost-effective solutions in the minimum amount of time. Novasep combines conventional chemistry with special technologies:

• hazardous chemistry,
• asymmetric synthesis, chiral resolutions,
• Highly Potent API (including ADC) handling in our SafeBridge® certified facility,
• cryogenic chemistry,
• biocatalysis,
• process chromatography (batch HPLC and SFC, continuous SMB, computer simulation)
• etc.

Our offering includes designing your process, as well as engineering, building, validating and operating manufacturing plants for your synthetic APIs.

http://www.novasep.com/synthetic-molecules/Synthetic-molecules-offering.asp.

OmegaChem Inc [ company website ]

OmegaChem Inc. is a Canadian privately owned company, located in Quebec City. Since 1988, our mission is to supply the pharmaceutical industry with innovative fine chemical products and offer a wide range of services: custom synthesis, contract research, sourcing for rare quality chemicals. Our main field of expertise is the development and production of fluorinated products such as natural amino acid derivatives and functionalized heterocycles. OmegaChem focuses on investing in research and development in order to provide innovative compounds and reagents to the market. We employ over 60 scientists, mostly Ph.Ds. who are highly trained in organic synthesis. OmegaChem has recently inaugurated a new facility that hosts the corporate headquarters and laboratory areas with state of the art equipments.

OmniChem [ company website ]

OmniChem offers high-technology know-how, quality, flexibility and trustworthiness, based upon personnel of the highest quality, on adapted equipment and multi-purpose facilities. Each project is carried out in close and frank co-operation with the customer’s technical staff and coordinated through an efficient project management system.

Onyx Scientific [ company website ]

Onyx Scientific offers Custom Synthesis and Manufacturing services from Med-Chem to Commercial Programs. We offer customers “BEST OF BOTH WORLDS” in executing early phase programs from our UK sites and late phase programs from FDA/MHRA approved India locations. Onyx Scientific offers FTE services, Process R&D, Solid State characterisation, Scale-up and manufacturing services. Chemistry capabilities include chiral synthesis, steroids and hormones development, biotinylation & heterocyclic compounds.

PharmaCore, Inc. [ company website ]

Since 2000, PharmaCore® has performed a variety of chemistry services for leading pharmaceutical and biotechnology companies including: custom organic synthesis; cGMP scale-up; development of novel molecular building blocks; chemical process research and development; and medicinal chemistry services.  Our success is due to our competitive pricing, our unwavering commitment to customer service and to the talent and experience of our scientists, most of whom hold doctorates in organic chemistry.

PharmaZell [ company website ]

PharmaZell offers to its clients standard and custom made APIs and intermediates as well as all chemical, pharmaceutical development services and regulatory activities required to bring a pharmaceutical product to the market. PharmaZell develops innovative processes for APIs and Intermediates through its R&D groups that cover all scales from laboratory to commercial production. Through the acquisition of GEA, PharmaZell provides fully vertically integrated development programmes from API to finished dosage form including regulatory documentation, procedures and strategies.

Piramal Healthcare [ company website ]

Pharma Solutions is the Contract Development and Manufacturing division of Piramal Healthcare (erstwhile known as Nicholas Piramal) Pharma Solutions is one of the very few Contract Manufacturing Organizations (CMOs) that can provide end-to-end support for bringing a drug to market or managing the life cycle of a launched drug. We offer Clinical Phase API synthesis and Formulations Development services and scale up to Commercial API and Finished Dosage form supply.

Ricerca Biosciences [ company website ]

Ricerca is the only North American CRO to offer the unique IP-IND^SM concept to pharmaceutical and biotechnology companies. The site encompasses all discovery and development services required to bring a target or drug candidate to a complete IND submission. The ability to perform both chemistry (medicinal chemistry, process chemistry, cGMP API kilo-lab and pilot plant production, complete analytical) and biology (DMPK, ADME, full toxicology, safety pharmacology, animal efficacy models, bioanalytical) as well as report writing and regulatory services at one site makes Ricerca the provider of choice for virtual, small, and medium-sized pharmaceutical companies seeking a successful IND submission.

Sanofi CEPIA [ company website ]

Sanofi – CEPiA Sales is a Sanofi activity dedicated to contract manufacturing services. By employing its exhaustive industrial resources and other resources expected of big pharma, CEPiA provides its clients with “fast to market” solutions. CEPiA offers API and custom synthesis expertise in both small and large molecule chemistry from lab scale through commercial quantities. Additionally, CEPiA offers its extensive drug product capabilities including solids, semi-solids, liquids and parenteral products in vials, pre-filled syringes and devices including formulation optimization, clinical and commercial manufacturing.

Sarmont [ company website ]

SARmont is a trusted provider of medicinal chemistry design and lead optimization services. Our scientific team is led by Dr. John Talley, the inventor of Celebrex and seven other drugs that successfully reached the market. Our team works collaboratively with clients to identify and optimize proprietary investigational new drug (IND) candidates. We use a combination of rational drug design, insightful activity trend analysis, informed interpretation of medical need, and careful synthetic planning. To assure cost efficient compound synthesis we utilize a respected high quality strategic CRO partner in India, Escientia. All IP is retained by our clients – we streamline and accelerate your drug design process, through effective project management of the design, synthesis and lead optimization process.

Scynexis [ company website ]

SCYNEXIS delivers integrated, efficient and innovative drug discovery and development solutions to our global health and pharmaceutical partners. Our record of success is exemplified by the delivery of 11 pre-clinical drug candidates over the last five years. Milestone payments have resulted as these compounds progressed through development at our partners. Our fully-integrated contract research solutions include medicinal chemistry, advanced biological screening, in vitro pharmacology and ADMET, DMPK, bioanalytical and analytical chemistry, process chemistry, and cGMP manufacturing. The SCYNEXIS process chemistry department recently passed a general inspection and pre-approval inspection (PAI) by the FDA in support of a customer’s NDA. Our expertise is offered on a fee for service basis or may be conducted in a shared risk arrangement. SCYNEXIS’ teams are tailored to be especially effective in moving customer projects from concept to clinic, utilizing powerful proprietary technologies such as the HEOS® Data Management and Collaboration Software Suite and the MEDCHEM-FACTORY® High-Throughput Synthesis and Purification Platform. Founded in 2000, SCYNEXIS is located in Research Triangle Park, N.C. SCYNEXIS is registered with both the FDA and DEA.

Senn Chemical [ company website ]

Established in 1963, Senn Chemicals is a premier business partner in the development, scale up, and manufacture of carbohydrates, fine chemicals and peptides: peptidomimetics, glycoeptides, lipopeptides for pharmaceutical, biotechnology, cosmetic and diagnostic clients. Senn offers products via catalog sales, and upon custom manufacturing under cGMP to meet specific customer requirements.

Siegfried USA [ company website ]

Siegfried is a globally active, independent Swiss company. As a supplier and service provider for the worldwide pharmaceutical industry, we concentrate on the development and production of pharmaceutical drug substances and customer-manufactured finished drugs, and offer all related services. We focus on maintaining the highest level of competence, working together with our clients as partners. Our specific know-how in process development, chemical and pharmaceutical production, and managing complex outsourcing projects is used to contribute significantly to the success of our customers.

Solid Form Solutions [ company website ]

Solid Form Solutions is a world leading contract research organization (CRO) providing the pharmaceutical industry with polymorph, salt and co-crystallisation screening services. Our services also include crystallisation development, particle development as well as basic physical properties / developability characterisation. Our aim is to be flexible, understand our client’s solid form problems and recommend workable solutions. Whether our expertise is required to deliver a solid form screening program or tackle specific problems encountered during drug manufacture, Solid Form Solutions will provide an unrivalled service.

Solvias [ company website ]

Solvias is a privately held company located in Basel/Switzerland. With over 300 highly qualified employees, Solvias supports the research and development of new drug substances and the optimization of manufacturing processes for pharmaceutical, biotechnology and life science companies worldwide. Customers benefit from a wide range of experience in the following areas: Chemical Development and cGMP Manufacturing , Catalysis, Analytical Services, Process analytical technologies and, Polymorphism, salts and crystallization. All analytical services are cGMP-approved by the FDA and Swiss authorities.

Spectrum Chemical [ company website ]

Spectrum Custom Synthesis, a Division of Spectrum Chemical Mfg. Corp., has more than 40 years of experience as an innovative chemistry outsourcing partner for pharmaceutical and biotechnology customers. We provide a full range of US-based contract research and manufacturing services, including the custom synthesis of new chemical entities (NCE’s) through the commercial cGMP manufacture of API’s, excipients, DEA Controlled Substances (Schedules II-V) and their chemical intermediates. Spectrum Custom Synthesis offers our customers a unique experience, combining the personalized service and responsiveness of a mid-size company with the resources, logistics, and technical depth of much larger companies.

Spectrum also manufactures and distributes over 15,000 chemical products, including API’s, excipients, biochemicals, dietary & nutritional supplements, cosmetic ingredients, analytical reagents, and chemical solutions. Visit us at SpectrumChemical.com and request a copy of our NEW 2012-2013 Spectrum Bulk Fine Chemicals Catalog, containing over 3,300 products available in production quantities, including 1,200+ monograph chemicals for food and drug use.

Sphinx Scientific Laboratory Corp. [ company website ]

Sphinx Scientific Laboratory Corporation located in Sycamore, IL, a one hour drive from Chicago, has grown into a modern CRO fully equipped with state of art facilities. The services include custom synthesis, contact research services and process development. The facilities in China occupy 43,000 square feet of space including R&D labs, kilo labs, and analysis center. The analysis center is equipped with 400MHz NMR, LC-MS, GC-MS, and HPLCs. Reactors in Kilo-labs range from 50 to 200 liters with the temperature control between -80 °C and 200 °C. The unique Sphinx Management, that is projects run 24 hours a day, 7 days a week and chemists work 8 hours a day, 5 days a week, guarantees the shortest lead time at the lowest cost.

SST Corporation/Fermion [ company website ]

SST is a full-service pharmaceutical agency that represents world-class manufacturers of active pharmaceutical ingredients (APIs) and fine chemicals and intermediates (FCIs). Our audited network of global suppliers provide gram to commercial-scale production of APIs and FCIs, as well as custom synthesis. We bring substantial added value to this service with in-depth regulatory and technical expertise and processing, supply-chain management and other services.

Sygnature CSL [ company website ]

Sygnature CSL is a leading provider of premium discovery chemistry services (medicinal, synthetic and computational chemistry). Founded in 2004, the company has built an enviable reputation for delivering ‘top tier’ science coupled with high value and quality. Sygnature has a strategic alliance with Cyprotex to deliver integrated discovery chemistry/DMPK services.

Syncom B.V. [ company website ]

Syncom is a privately owned company established in 1988. It has grown rapidly in recent years and currently employs 130 chemists 75 of whom have PhD degrees and the rest a masters degree or equivalent. About 95% of the work carried out is for the pharmaceutical industry and the other 5% is devoted to the synthesis of organic materials. The company is involved in Medicinal chemistry and drug discovery and synthetic support for chemical development and process research. The major focus is on synthesis for discovery chemistry support. Syncom is located in the Groningen in The Netherlands. Our business is with big farma companies, medium sized and biotech companies form Europe and the US.

The Chemistry Research Solution [ company website ]

The Chemistry Research Solution is a contract research organization located in Bristol, PA, geared towards providing exceptional chemistry services to pharmaceutical, and biotech companies as well as government and academic research institutes. The mission of TCRS is to assist its clients in their product development programs by utilizing the expertise of its highly trained staff in the areas of complex organic synthesis, medicinal chemistry, and process development to successfully meet their goals. The staff of TCRS is comprised of chemists coming from major pharmaceutical companies and their broad knowledge of the industry has been, and continues to be, of great value to those members of the chemical research community who have used our services. Please visit us at Booth # 71.

Tosoh USA [ company website ]

The Tosoh Fine Chemical Group provides halogen expertise, building block chemicals on commercial scale, extensive coupling technologies and custom synthesis, including GMP, from small scale to MT. These are only a few of the many elements that the Tosoh Fine Chemical group of companies bring to your chemical development and commercial production programs. Along with technology, the group brings a large array of equipment resources to help you to meet your product targets. Throughout our facilities in Japan we offer a total of 158 reactors up to 10,000 L. With some possessing temperature capabilities to -100C and many GMP, we have the flexibility to address most any project.

Ubichem, Inc. [ company website ]

Ubichem Pharma Services/Manufacturing provides a comprehensive range of small molecule chemistry services to support pharmaceutical development and manufacturing – process R&D, scale-up, cGMP API and commercial scale intermediates manufacture, and radiolabelling (non-GMP and GMP). We do all chemistry in Budapest, Hungary, an untapped low cost area within the EU with tradition and expertise in chemistry. We are particularly experienced with heterocyclics, sugar derivatives, organometallic, cryogenic and high temperature chemistry and chiral resolutions. Our current development projects involve a commercial scale continuous countercurrent extraction system, a 6kg/hour high temperature flow system, a cryogenic flow system being built in house and a phosgenation flow system based on triphosgene.

Zach System S.p.A. [ company website ]

ZACH – Zambon Chemicals is a major provider with 470 staff in 2 manufacturing sites at Lonigo (Veneto/Italy) and Avrillé (Western France) and HQ in Bresso/Milan. Both sites are FDA inspected and compliant with national and international regulations. Lonigo has 741 m3 capacity in 100 reaction trains for large volume APIs (> 500 tons/year), Avrillé has 100 m3 with its strategic role for clinical cGMP APIs and intermediates and complementary production. R&D focuses on scale-up and industrialization for cost effective processes. Continuous innovation leads to future processes in batch and continuous Ozonolysis, sophisticated solid state crystal analysis at unprecedented resolution. ZACH holds 480 patents (175 active). In a highly competitive business, large capacity and efficient process chemistry for APIs and advanced intermediates makes ZACH is an innovative part of the modern pharmaceutical Supply Chain to the patient.